Citrulline Malate is the commercial form of the alpha amino acid citrulline. It is used in performance enhancing supplements for athletes. It has reported antiasthenic effects, which means that it is effective against weakness or muscle fatigue. A scientific study was conducted where some subjects reporting fatigue, but without any disease symptoms, were given this substance. The results indicated that the ingestion of the substance not only resulted in a significant reduction in the feeling of fatigue but also led to a 34% increase in the ATP (the energy currency of the cells) production during exercise. The study also indicated that this substance takes an active part in the production of oxidative ATP.

Di-Creatine Malate is a compound made up of creatine salt that is bonded together with malic acid. It increases the availability of creatine in the body; this ensures the efficient absorption and use of creatine. The compound results in a greater production and quick replenishment of adenosine triphosphate or ATP. It helps in increasing strength in the cellular level that allows the production of explosive bursts of power. It also aids in increasing endurance by acting as lactic acid buffer. Di-Creatine Malate helps in the formation of muscle mass, decrease fat tissue, and improves cell volume. It also does not cause upset the stomach because it is easily absorbed by the intestine.

Magnesium Creatine Chelate can help runners in reaching physiological threshold later in exercise. With the formation of this molecule, creatine cyclization to creatinine in the stomach’s acidic pH can be prevented. Active creatine is provided to the bloodstream by chelate. It also provides magnesium, involved in more systems of energy production than creatine. As compared to creatine monohydrate, Magnesium Creatine Chelate is more beneficial in the enhancement of lean muscle mass. It not only supports energy levels in the body but also increase power and strength. Magnesium Creatine Chelate is also useful in regard to performance nutrition. According to various studies, supplementation of Magnesium Creatine Chelate is beneficial on sets of maximal effort isokinetic knee extensions. It is more bioavailable as compared to creatine monohydrate and magnesium oxide.