Bioperine or black pepper, which is a common spice, has medicinal properties. It is a tropical plant and India is the largest producer of Piper Nigrum. It possesses anti-bacterial and anti-inflammatory properties. It acts as an antioxidant agent also. Black Pepper contains essential oil, which acts against intestinal flatulence and also stimulates sweating and urination. The essential oil found in Piper Nigrum stimulates stomach cells to produce HCl acid, which helps in digestion. Piper Nigrum also helps in absorption of certain essential micronutrients like coenzyme Q-10, beta-carotene and EGCG. Pepper has its contribution in Ayurvedic medicines also. Pepper seeds are used to prepare sinusitis relieving medicines. It also used for sore throat and dry cough.

Caffeine is extracted from coffee and tea during the process of decaffeination. Caffeine Anhydrous can be produced from dimethyl urea and malonic acid. It stimulates the central nervous system, enhancing the focus, concentration, and alertness, and warding off drowsiness. It is a mild diuretic and can also increase the metabolism. It increases the energy level and reduces fatigue. Aside from increasing mental alertness, it also helps in maximizing weight loss training. It stimulates the metabolism that helps the body to burn fat faster and uses the fat as energy. It also provides physical energy and delays the onset of fatigue.

Green Tea Extract comes from green tea leaves and has been shown to be a very effective supplement for many common ailments ranging from minor to life threatening. Green tea extract is known for its strong antioxidant qualities, making it popular amongst those who take an active role in ensuring their good health. In fact, green tea extract has twenty times more antioxidants than the same portion of Vitamin C, another clouted supplement for health aficionados. In addition to antioxidants, green tea extract is effective at fighting carcinogens and inflammation. Green tea extract is best known for fighting cancer when combined with other methods, for reducing inflammation, and for encouraging overall good physical health.

Raspberry Ketones- Red raspberries contain a phenolic compound, which is the main aroma in red raspberries. This raspberry ketone is being used in cosmetics and perfume industries, but also as a food additive. While the use as a weight loss agent has not yet been clinically tested on human subjects, preliminary research in lab mice has shown that raspberry ketones in high doses show a norepinephrine induced lipolysis. This leads to the effect that even a diet high on fats did not result in higher body weight. This fact has immediately led to the embrace of raspberry ketones by the weight loss and body building communities, despite the fact that raspberry fruits would be much healthier, containing ellagic acid, catechins, salicylic acid, and various other polyphenols, besides large quantities of Vitamin C.

Synephrine is an adrenergic amines and stimulant with beta-3 receptors. It functions to increase metabolic rate with no effect to heart rate or blood pressure. Synephrine releases adrenaline and noradrenalin in the adipose tissue and the liver. Stimulation of the beta-3 receptor sites to educe the breakdown of fat. It can be added to the group of stimulants, to which belong such supplements as caffeine or ephedrine. Can be used to boost energy, suppress appetite and enhance metabolic rate to burn more calories and increased the energy, but it does not cause so undesired negative cardiovascular effects. Its active ingredients include gelatin, cellulose, and silica and magnesium strearate. Its weight loss abilities are associated with citrus aurantium (synephrine) supplements which give it the stimulant like effects of the alkaloids.

Tyramine is derived from tyrosine, which is an amino acid. It is a monoamine compound, believed to be able to affect the release of dopamine, epinephrine and norepinephrine, which can be stored as monoamines. Tyramine is widely present in animals and plants alike, where it is produced by fermentation or decay, for instance pickled, aged, smoked and otherwise fermented foods like beef and poultry, but also fish and pork; it is also in chocolate, alcoholic drinks, cheeses, except some white cheeses, yoghurt, sour cream, but also bananas, pineapples and raspberries, to name a few. The adrenaline release instigated by the intake from tyramine is supposed to induce fat loss by increasing the glucose absorption by the muscle mass, making it a popular supplement with the body building aficionados.

Yohimbe contains an alkaline called yohimbine. It releases a hormone that stimulates sexual organs and blood flow in the genitals known as norepinephrine. Yohimbe is known treatment for sexual dysfunctions such as male impotence. It also has aphrodisiac property that improves the libido for both men and women. Yohimbe also helps in weight loss by increasing lypolysis by enhancing the excretion of norephinephrine. It also has antioxidant properties. It may also improve and alleviate exhaustion and feebleness. Yohimbe also helps alleviate the mood by blocking the enzyme called monoamine oxidase that may cause depression. Yohimbe also causes vasodilation that helps lower blood pressure.