Caffeine is the most widely used legal stimulant of the central nervous system and is also used in Designer Supplements Adrenalean, with characteristics that have been described as restoration of alertness and removing from drowsiness. Coffee, Tea, many soft drinks and energy drinks as well as nutrition supplements have this ingredient, which is a psychoactive substance, a xanthine alkaloid that can act as a adenosine receptor antagonist, as well as a phosphodiesterase inhibitor. Although regular use of caffeine seems to have nootropic effects, enhancing cognitive abilities, it also is known to provide long term effects on the nervous and cardiovascular system, like in one study it was proven that people with normal to low blood pressure have the possibility of developing a heart disease significantly reduced, as well as the chance of getting the Parkinson’s disease.

Evodiamine has been used in Chinese medicine and by Chinese herbalists for centuries for weight loss purposes. It is an extract from a plant, Evodia or Tetradium, actually a tree genus of the family Rutaceae. The bee bee tree, as it is called besides Euodia and Evodia, provide a bioactive alkaloid that the Chinese have nicknamed Wu-Chu-Yu. This extract not only can interact with UCP1, a thermogenic protein, which as a consequence burns energy as heat, but also has shown in studies on mice to reduce the fat uptake. Evodiamine seems to increase the resting temperature of humans, whereby increased fat and calories are burned in order to supply the heat. Deemed a breakthrough in thermogenesis, evodiamine is subject of several clinical studies.

Hordenine has antibacterial and antibiotic properties and is another weight loss agent that also stimulates the central nervous system.

L-Huperzine A is a naturally occurring plant alkaloid which may be found in the Huperzia serrata extract. It has been used in China for many centuries for its medicinal properties. It is used for treating fever. It also has anti-inflammatory property that can help reduce the swelling. It is also a potent supplement for boosting the memory, learning, focus and concentration. It works by inhibiting the chemical acetylcholinesterase from breaking down acetylcholine which plays an important role in the transferring and storing information throughout the brain. L-Huperzine also helps in the treatment of the disease myasthenia gravis (MG), an autoimmune disease. It also helps prevent dementia and Alzheimer’s disease.

Methylaricaiden is an alkaloid that may be obtained from betel nut, the fruit of a palm tree. It is known to be a potent stimulant that improves the alertness, focus and concentration. It enhances the mood, and fights depression. It is also a mild laxative that helps prevent water retention, cleans the body, and aids in weight loss. It alleviates the symptoms of rheumatism and arthritis. It also helps treat headaches and fever. Methylarecaiden has prevents and kills parasites in the body. It also promotes wound healing. It also has antioxidant properties that scavenges free radicals and prevent it from causing cell damage.

Phenylethlamine HCL is a salt of phenylethylamine. It is a crystalline solid and is formed by treating phenylethylamine with HCl. Its IUPAC name is 2 phenylethylamine HCl. The scientific name elucidates its chemical structure. It is an aromatic compound meaning that it has a basic benzene ring. It further has a two carbon chain attached at position 2 of the ring and the chain terminates in an amino group. It occurs naturally in some foods like chocolates but the food item might get metabolized too quickly sometimes for it to have a significant effect on the body. This substance has quite profound effects on the level of dopamine in the central nervous system, provided it passes the blood brain barrier. It increases dopamine level and at the same time inhibits dopamine transmitters resulting in a buildup of dopamine in the brain. While excessive levels of dopamine in the CNS are not healthy, the neurotransmitter does regulate cognition, mood, voluntary movement and other brain functions.

Quercetin, a bioflavonoid derived mostly from blue-green algae. Quercetin is a strong antioxidant commonly found in onions, wine and tea.

Synephrine HCL is used in traditional Chinese medicine for various purposes such as appetite suppression and fat loss. Synephrine HCL is associated with ephedrine and ephedra and this is the reason that they get focused energy. It is as well noted that the users do not have a feeling of their energy getting crashed. Synephrine HCL is mainly used to aid fat loss, appetite suppression and energy. Each capsule of Synephrine HCL contains 20 mg and each container has 100 capsules. Synephrine HCL is taken as a dietary supplement prior to meals. Synephrine HCL can be taken three times everyday. However, individuals below 18 are not recommended to use. Even nursing or pregnant women are not recommended for use. It is best to take this after consulting a healthcare professional so that if one is diagnosed with heart or kidney disease, renal or recurrent headaches, asthma, depression or any such and is continuing with those medicines may or may not be advised to take Synephrine HCL.