Caffeine is extracted from coffee and tea during the process of decaffeination. Caffeine Anhydrous can be produced from dimethyl urea and malonic acid. It stimulates the central nervous system, enhancing the focus, concentration, and alertness, and warding off drowsiness. It is a mild diuretic and can also increase the metabolism. It increases the energy level and reduces fatigue. Aside from increasing mental alertness, it also helps in maximizing weight loss training. It stimulates the metabolism that helps the body to burn fat faster and uses the fat as energy. It also provides physical energy and delays the onset of fatigue.

Citrus Aurantium is a fruit from the citrus family. Although later replaced by the sweet orange in recognition, it has retained many practical uses both in home remedies and in food. Citrus Aurantium boosts up the metabolism, which converts fat deposits into energy. Extensive use may help to control weight and hold back the effects of obesity. It can work as an appetite suppressant to restrain overeating. Citrus Aurantium can help to reduce chest congestion and coughs. Citrus Aurantium is a potent energy booster.

Synthetic Guggulsterones improve the metabolism by increasing the thyroid hormones that influences the triiodothyronine (T3) hormones. It also activate the lypolytic enzymes the helps the burning of fats. Synthetic Guggulsterones is effective for weight loss without raising the heart rate. It also helps maintain the ideal cholesterol level within the normal range. It decreases the LDL cholesterol and triglyceride (TG) levels. Synthetic Guggulsterones also acts as a potent anti-inflammatory agent because of its myrrhanol A content. It also helps reduce acne because it contains tetracycline that is commonly used as an antibiotic in treating acne. It also reduces oxidative stress by decreasing the lipid peroxidation.

Yohimbe is an alkaloid and the active ingredient of a medicinal herb also known as Pausinystalia yohimbe, formerly named Corynanthe yohimbe. It is noted as a stimulant drug and also as an aphrodisiac. While the medicinal community has conducted numerous studies of yohimbe in conjunction with sexual dysfunctions, in veterinary medicine, yohimbine is employed as the antidode to anesthesia stemming from the drug xylazine in large and small animals. In recent times, yohimbine has been found to instigate fat loss in athletes when taken orally. There are also some formulations available, for a significant price, where yohimbine can be directly applied transdermally to adipose tissue, leading to a local reduction. This application is still in experimentation and should not be used without professional assistance.