Bioperine is derived from the extract of Piper nigrum L (black pepper) or Piper longum L (long pepper). Bioperine activates the thermogenesis process that generates energy at the cellular level. This process also helps in burning of fats. It also increases the absorption of nutrients and vitamins. It ensures that the body benefits and is able to efficiently use the nutrients from the food. It also boosts the metabolism that makes it effective in weight loss and maintenance. Because of the boost in metabolism, it also provides the body an increased supply of energy. It also aids in the proper digestion.

L-Arginine is a very important amino acid that is required by the body for a number of functions. One of the main functions of L-Arginine is its ability to rid the body of ammonia, which is a waste product. It is also used in the manufacture of nitric oxide, which helps to relax the blood vessels, thereby increasing the flow of blood and reducing the chances of a heart attack. It is advised that supplements of L-Arginine should not be administered following a heart attack for fear that it could possibly aggravate cardiac shock. L-Arginine is being used in treating people with erectile dysfunction, as it relaxes the blood vessels surrounding the penis. It is also used in treating migraine and blood pressure.

L-Ornithine is an amino acid that is commonly used in various nutritional supplements. It aids the metabolism and promotes the excretion of growth hormones. It helps develop lean muscles and burns body fat. It also boosts the immune system function and protects the body from acquiring illness caused by infections. It also aids in detoxifying the body from toxins that may cause serious diseases. L-Ornithine promotes the development of muscles and prevents catabolic activity. It benefits the elderly because it prevents muscle degeneration. It helps burn fats for energy supply and promotes formation of muscles. It also helps in regulating blood sugar and blood cholesterol level.

Magnolia Bark usage has been adopted from traditional Chinese medicine, where it was being used as an anti depressant. In conjunction with other ingredients, like Pinellia ternata, Poria cocos and Zingiber officinale, it has displayed effects that rival the ones of Prozac. Houpu, which is how Chinese call magnolia officinalis bark, contains polyphenolic compounds, mangolol, which is a bioactive compound with antifungal properties; and honokiol, a biphenolic compound which is known as an anxiolytic, anti-emetic, anti-depressant, antithrombotic and anti-bacterial. Honokiol in particular is a very potent anti-tumorigenic and neurotrophic compound, used to combat melanoma, leukemia, myeloma and sarcoma, as well as a multitude of cancers. It is also a known promoter of neurite outgrowth and has neuroprotective effects. There are no adverse effects known.

Melatonin is a hormone secreted by the pineal gland in the brain regulating other hormones and circadian rhythm in the body. It determines when we sleep and when we awake. Activated by darkness, it remains suppressed during the day. Melatonin levels are age related, with children having high levels which diminish with increasing age leading to disturbed sleep in the aged. It controls the onset of menstruation and menopause in women. Melatonin is known for its antioxidant properties. Melatonin supplements prevent insomnia, improve the quality of sleep and increase morning alertness. It is known to stimulate bone growth, prevent headaches and migraines and reduce depression and anxiety. It reduces sleep disturbances in children with ADHD. Reduced melatonin production leads to an increased risk of cancer.

N-Acetyl-5-Methoxytryptamine is a naturally occurring compound with chemical formula C13H16N2O2 and Mol. Mass 232.278 g/mol. Its CAS number is 73-31-4. It naturally occurs in animals, plants, and microbes. N-Acetyl-5-Methoxytryptamine is also commonly known as Melatonin. It’s primarily used in medicine and supplements to treat circadian rhythm sleep disorders, and improve the quality of sleep. Research also shows that it can be used for the treatment of certain forms of insomnia. It is also shown to exert powerful antioxidant activity in body, and a small immunological effect is also observed. Low levels of N-Acetyl-5-Methoxytryptamine can cause sleep and autism spectrum disorders.

Piper Nigrum(Black Pepper) or black pepper, which is a common spice, has medicinal properties. It is a tropical plant and India is the largest producer of Piper Nigrum. It possesses anti-bacterial and anti-inflammatory properties. It acts as an antioxidant agent also. Black Pepper contains essential oil, which acts against intestinal flatulence and also stimulates sweating and urination. The essential oil found in Piper Nigrum stimulates stomach cells to produce HCl acid, which helps in digestion. Piper Nigrum also helps in absorption of certain essential micronutrients like coenzyme Q-10, beta-carotene and EGCG. Pepper has its contribution in Ayurvedic medicines also. Pepper seeds are used to prepare sinusitis relieving medicines. It also used for sore throat and dry cough.

Ziziphus Jujuba is also known as the Indian Jujube. These fruits are applied on cuts and used for pulmonary ailments and fevers. The dried ripe fruit is also used as a mild laxative. They are a rich source of protein, calcium, thiamine, citric acid, iron and phosphorus. The dried leaves of the plant are used in poultices for liver trouble, asthma and fever. The juice of the root bark is used to alleviate gout and rheumatism. The flowers are even used to make a lotion for the eyes.