Chromium Polynicotinate, which is a form of chromium, an essential trace mineral that is needed for the body's production of insulin. Insulin is a hormone that stabilizes the body's blood sugar level.

Guarana has in recent times received widespread popularity because of an energy drink. It is actually a climbing plant in the family related to maple and is native to the Amazon region, predominantly in Brazil. It is a flowering plant with big leaves, but the fruit is the most prominent component, not bigger than a coffee bean. Guarana fruit has about the double content of caffeine when compared to the coffee bean. Besides the cognitive and fatigue reducing effects of caffeine, guarana displays also other interesting properties, such as the assistance in a weight loss program; namely, guarana affects the perception of the satiation, making the person feel full sooner. Further antioxidant and antibacterial effects have been noted as well. In combination with linoleic acid, guarana has shown fat cell reduction effects in mice.

Gymnema Sylvestre is an herb that has shown to reduce blood sugar and is used by some to reduce sugar cravings as it seemingly reduces the sugar taste when placed in the mouth.

Hoodia Gordonii, which although popular, has no published randomized controlled trials in humans to show hoodia is safe or effective in pill form. One study published in the September 2004 issue of Brain Research found that injections of p57 (The Active ingredient in Raw, Fresh Cut Hoodia, not dried) into the appetite center of rat brains resulted in altered levels of ATP, an energy molecule that may affect hunger. The animals receiving the P57 injections also ate less than rats that received placebo injections. However, this was an animal study and INJECTIONS IN THE BRAIN are very different from oral consumption, so it cannot be used to show that oral hoodia can suppress appetite in humans. Hoodia Gordonii is a succulent (a cactus of the aloe family) found in the Kalahari desert of South Africa. Most Hoodia Gordonii products contain very little, if any of the active ingredient needed to suppress hunger. Real Hoodia is very rare and is even an endangered plant. Most importantly, Hoodia has only demonstrated any effect in fresh, raw pieces of the plant. The effectiveness of powdered Hoodia has yet to be shown and may actually increase hunger. It's main use is as a cheap alternative to the more expensive weight loss herbs, which are the only alternative left after the banning of ephedra. Most supplement manufacturers can not use the more expensive weight loss herbs because it will result in a product that would be too expensive to compete with other more popular inexpensive diet supplements.